Organic photoelectrochemical transistor detection of tear lysozyme
نویسندگان
چکیده
A high-performance organic photoelectrochemical transistor (OPECT) is developed by synergizing a light-sensitive aptamer/CdS QDs/Ti wire gate photoanode with PEDOT:PSS-based device towards detection of the tear biomarker lysozyme.
منابع مشابه
Immunoassay of tear lysozyme in conjunctival diseases.
The tear lysozyme content in 111 normal subjects and in 159 patients with various conjunctival diseases was determined by a single radial immunodiffusion technique. Tear lysozyme level in normal people was 1.33/mg/ml. (SI conversion: mg/ml = g/l.) The mean tear lysozyme levels in patients with chronic irritative conjunctivitis (0.97 mg/ml) and nutritional deficiency with epithelial xerosis (0.7...
متن کاملRabbit tear proteins. I. Detection and quantitation of lysozyme in nonstimulated tears.
Rabbit tear lysozyme was detected in low concentration in rabbit tears collected without any stimulation. Quantitation of rabbit tear lysozyme was found possible through the use of sensitive techniques that measure its specific enzymic activity on the bacterial cell walls of Micrococcus lysodeikticus. Rabbit tear lysozyme has an electrophoretic mobility identical to that of hen egg-white lysozy...
متن کاملImmunoassay of tear lysozyme in acute adenovirus conjunctivitis.
The tear lysozyme levels were measured by immunoassay in 92 healthy subjects and 98 patients with acute adenovirus conjunctivitis. They were found to be significantly decreased during the acute phase of the disease. The extent of this decline in the tear lysozyme level was correlated with increased severity of disease. There was no significant difference in the tear lysozyme level in viral isol...
متن کاملQuantitative tear lysozyme assay in units of activity per microlitre.
An accurate method of assaying the tear lysozyme concentration in units of activity/mul has been developed. Normal physiological levels which vary with age have been determined. It has been demonstrated that measurement of the volume of tear fluid collected and assay with a calibrated standard are essential for the accurate determination of the precise concentration of lysozyme in the tear flui...
متن کاملInteraction of tear lipocalin with lysozyme and lactoferrin.
The interaction of human tear lipocalin with lysozyme and lactoferrin was studied by electron paramagnetic resonance (EPR) spectroscopy. TL mutants I98C and F99C were spin labeled with MTSL and its derivative. The spectra demonstrated that at sites C98 and C99 the mobility of the nitroxides was reduced in the presence of lysozyme, lactoferrin, but not albumin. The reduced mobility was manifeste...
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ژورنال
عنوان ژورنال: Sensors & diagnostics
سال: 2022
ISSN: ['2635-0998']
DOI: https://doi.org/10.1039/d1sd00074h